SCHEMBL8675928

SCHEMBL8675928

CCCCCCCCCCC(CC(CC(C)C(C)(C)C)c1ccccc1O)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
CYSLTR2 Q9NS75 4/20 0.36
CYSLTR1 Q9Y271 4/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
CNR1 P21554 5/20 0.35
CNR2 P34972 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105325 1.00 TSHR (0.40) TSHRCYSLTR2CYSLTR1GABRA1GABRB2
SCHEMBL8674113 1.00 TSHR (0.40) TSHRCYSLTR2CYSLTR1GABRA1GABRB2
SCHEMBL106346 0.91 TSHR (0.41) TSHRCYSLTR2CYSLTR1GABRA1GABRB2
SCHEMBL106674 0.91 TSHR (0.42) TSHRCYSLTR2CYSLTR1GABRA1GABRB2
SCHEMBL1240633 0.89 TSHR (0.44) TSHRCYSLTR2CYSLTR1GABRA1GABRB2
SCHEMBL8673232 0.89 TSHR (0.44) TSHRGABRA1GABRB2CNR1CNR2
SCHEMBL8677677 0.87 TSHR (0.40) TSHRCYSLTR2CYSLTR1GABRA1GABRB2
SCHEMBL107936 0.85 TSHR (0.45) TSHRCYSLTR2CYSLTR1GABRA1GABRB2
SCHEMBL3967030 0.85 TSHR (0.49) TSHRGABRA1GABRB2
SCHEMBL105322 0.83 TSHR (0.50) TSHRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1146637-C Polymer composition and core-shell elastomer used therefor 三井化学株式会社 2004-04-21 CN disclosed
CN-1052022-C Polymer composition and core-shell elastomer for use in the composition MITSUI PETROCHEMICAL IND (JP) 2000-05-03 CN disclosed
CN-1215069-A Polymer composition and core-shell elastomer used therefor MITSUI CHEMICALS INC (JP) 1999-04-28 CN disclosed
US-5770655-A ACRYLATE MONOMER WITH MULTICYCLIC FUSED RING IN ESTER GROUP, OPTICAL FIBERS AND DISKS, CLARITY AND IMPACT STRENGTH, TETRACYCLODODECYL ACRYLATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-06-23 US disclosed
US-5574100-A ALPHA-OLEFIN-CYCLIC OLEFIN COPOLYMER, BUTADIENE-STYRENE COPOLYMER CORE, ALICYCLIC ACRYLATE SHELL MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-11-12 US disclosed
CN-1111658-A Polymer composition and core-shell elastomer for use in the composition MITSUI PETROCHEMICAL IND (JP) 1995-11-15 CN disclosed
EP-0671433-A1 Polymer composition and core-shell elastomer used therefor MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-09-13 EP disclosed