Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917053 | 0.83 | SRD5A1 (0.45) | SRD5A1SRD5A2 | |
| SCHEMBL915556 | 0.77 | SRD5A1 (0.46) | FPR2PROKR1MMP12MMP13SRD5A1 | |
| SCHEMBL916849 | 0.76 | SRD5A1 (0.49) | SRD5A1SRD5A2 | |
| SCHEMBL917127 | 0.75 | SRD5A1 (0.45) | SLC6A4SLC6A2SLC6A3SRD5A1SRD5A2 | |
| SCHEMBL917299 | 0.75 | SRD5A1 (0.44) | MMP12MMP13SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL917805 | 0.75 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL917798 | 0.75 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL915497 | 0.74 | SRD5A1 (0.42) | SRD5A1SRD5A2 | |
| SCHEMBL917242 | 0.74 | SRD5A1 (0.45) | SRD5A1SRD5A2 | |
| SCHEMBL918119 | 0.74 | SRD5A1 (0.43) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5730964-A | Method of treating sweat-related conditions | MERCK & CO., INC. (US) | 1998-03-24 | — | — | US | disclosed |