Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL16990721 | 0.80 | — | — | |
| Propene SCHEMBL27387917 | 0.75 | — | — | |
| Propene SCHEMBL8190454 | 0.74 | TSHR (0.33) | — | |
| Propene SCHEMBL8039600 | 0.74 | TSHR (0.33) | — | |
| Propene SCHEMBL30536991 | 0.74 | — | — | |
| Propene SCHEMBL4948068 | 0.74 | TSHR (0.33) | — | |
| Propene SCHEMBL193 | 0.74 | — | — | |
| Propene SCHEMBL342422 | 0.74 | — | — | |
| Propene SCHEMBL8064619 | 0.74 | — | — | |
| Propene SCHEMBL8431129 | 0.74 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5851389-A | Apparatus for removing a contaminant from a fluid stream | CSK TECHNICAL, INC. (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0475620-B1 | Microemulsion diesel fuel compositions and method of use | EXXON RESEARCH ENGINEERING CO (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0383522-B1 | Separation technique for oil ontaminated sludge | EXXON RESEARCH ENGINEERING CO (US) | 1995-01-25 | — | — | EP | disclosed |
| EP-0475620-A2 | Microemulsion diesel fuel compositions and method of use | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| EP-0383522-A1 | Separation technique for oil ontaminated sludge | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1990-08-22 | — | — | EP | disclosed |
| US-4938877-A | Unique and effective separation technique for oil contaminated sludge | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4764285-A | BLEND OF SULFONATED HYDROPHILIC AND ETHOXYLATED LIPOPHILIC SURFACTANTS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| US-4599250-A | COAL COIATED WITH SURFACTANT BLENDS | EXXON RESEARCH & ENGINEERING CO. (US) | 1986-07-08 | — | — | US | disclosed |