Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679159 | 0.89 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL4632115 | 0.85 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151496 | 0.84 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631500 | 0.79 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4664077 | 0.79 | EDNRA (0.88) | EDNRAEDNRB | |
| SCHEMBL4631412 | 0.77 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL27457244 | 0.77 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL4662705 | 0.75 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631408 | 0.74 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7791379 | 0.73 | EDNRA (0.77) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699191-B1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORP (US) | 1998-12-16 | — | — | EP | claimed |