Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.69 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.69 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.69 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895786 | 0.83 | CHRM1 (0.92) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL4152396 | 0.83 | CYP2D6 (0.70) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL13074241 | 0.82 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL4556740 | 0.82 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL4919819 | 0.82 | CHRM1 (1.00) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL27056694 | 0.82 | CHRM1 (1.00) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL6579859 | 0.82 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL4572894 | 0.82 | CHRM1 (1.00) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| Hydrochloric Acid SCHEMBL11205630 | 0.81 | CYP2D6 (0.68) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL8671530 | 0.81 | CHRM1 (0.78) | CHRM1CHRM2CHRM4CHRM3SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5718912-A | Muscarine agonists | MERCK & CO., INC. (US) | 1998-02-17 | — | — | US | disclosed |