Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632649 | 0.85 | PTPN11 (0.74) | PTPN11PTPN1MAOAMAOBS100A4 | |
| SCHEMBL12670453 | 0.82 | PTPN11 (0.70) | PTPN11PTPN1MAOAMAOBHSD17B3 | |
| SCHEMBL12670273 | 0.82 | PTPN11 (0.70) | PTPN11PTPN1MAOAMAOBHSD17B3 | |
| SCHEMBL12670452 | 0.79 | PTPN11 (0.65) | PTPN11PTPN1MAOAMAOBS100A4 | |
| SCHEMBL26614363 | 0.78 | PTPN11 (0.64) | PTPN11PTPN1MAOAMAOBHSD17B3 | |
| SCHEMBL10877387 | 0.77 | PTPN11 (0.62) | PTPN11PTPN1MAOAMAOBHSD17B3 | |
| SCHEMBL27721368 | 0.73 | PTPN11 (0.56) | PTPN11PTPN1ALDH1A1MEN1KMT2A | |
| SCHEMBL27750430 | 0.73 | PTPN11 (0.56) | PTPN11PTPN1ALDH1A1IDO1 | |
| SCHEMBL28302837 | 0.72 | PTPN11 (0.56) | PTPN11MAOAMAOBHSD17B3ALDH1A1 | |
| SCHEMBL23167045 | 0.71 | PTPN11 (0.54) | PTPN11PTPN1MAOAMAOBHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029273-A | Compositions and methods for activating immune cells | MDX管理有限责任公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4680215-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING ADVERSE EFFECTS OF THERAPIES | MDX Management LLC (US) | 2026-01-21 | — | — | EP | claimed |
| US-20250333698-A1 | SIRPa DEFICIENT MACROPHAGES FOR TREATING CANCER | UNIV GEORGIA STATE RES FOUND (US) | 2025-10-30 | — | — | US | claimed |
| EP-4583855-A1 | SHP-1 INHIBITORS FOR TREATING CANCER | MDX Management LLC (US) | 2025-07-16 | — | — | EP | claimed |
| US-20250205337-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING IMMUNE CELLS | MDX MAN LLC (US) | 2025-06-26 | — | — | US | claimed |
| CN-119609942-A | Drum worm grinding wheel few-axis point trimming method | 重庆大学 | 2025-03-14 | — | — | CN | claimed |
| CN-119562818-A | Compositions and methods for activating immune cells | MDX管理有限责任公司 | 2025-03-04 | — | — | CN | claimed |
| WO-2025038745-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING IMMUNE CELLS | MDX MANAGEMENT LLC (US) | 2025-02-20 | — | — | WO | claimed |
| EP-4499117-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING IMMUNE CELLS | MDX Management LLC (US) | 2025-02-05 | — | — | EP | claimed |
| US-20240424019-A1 | SHP1 MODIFIED DENDRITIC CELLS AND EXTRACELLULAR VESICLES DERIVED THEREFROM AND ASSOCIATED METHODS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-12-26 | — | — | US | claimed |
| WO-2023060163-A2 | SHP1 MODIFIED DENDRITIC CELLS AND EXTRACELLULAR VESICLES DERIVED THEREFROM AND ASSOCIATED METHODS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-04-13 | — | — | WO | claimed |
| EP-4157292-A1 | HYPOXIA-RESISTANT NATURAL KILLER CELLS | ONK Therapeutics Limited (IE) | 2023-04-05 | — | — | EP | claimed |
| CN-115803092-A | SIRP alpha deficient macrophages for the treatment of cancer | 乔治亚州立大学研究基金公司 | 2023-03-14 | — | — | CN | claimed |
| EP-4139003-A1 | SIRPa DEFICIENT MACROPHAGES FOR TREATING CANCER | Georgia State University Research Foundation, Inc. (US) | 2023-03-01 | — | — | EP | claimed |
| CN-114617861-A | Application of TPI-1 and derivatives thereof in preparation of anti-coronavirus medicines and medicines | 中国科学院大连化学物理研究所 | 2022-06-14 | — | — | CN | claimed |
| CN-110738353-B | Prediction method and system based on human-water coupling mutual feed system dynamic evolution model | 华中科技大学 | 2022-05-20 | — | — | CN | claimed |
| US-20220151921-A1 | MONOCYTE-SELECTIVE DRUG DELIVERY SYSTEM USING SINGLE-WALLED CARBON NANOTUBES TO INDUCE EFFEROCYTOSIS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-05-19 | — | — | US | claimed |
| CN-114360251-A | Multidimensional comprehensive traffic safety index calculation method based on traffic safety influence | 陕西世纪高通科技有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-114220268-A | Method and system for carrying out optimal police dispatch based on road safety index | 济南市公安局交通警察支队 | 2022-03-22 | — | — | CN | claimed |
| WO-2021217038-A1 | SIRPα DEFICIENT MACROPHAGES FOR TREATING CANCER | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240424019-A1 | SHP1 MODIFIED DENDRITIC CELLS AND EXTRACELLULAR VESICLES DERIVED THEREFROM AND ASSOCIATED METHODS | PTPRCAP, PTPRF, PTPRM | PTPN11 15/4885PTPN1 6/4885MAOA 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.