Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675227 | 0.70 | TSHR (0.47) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL5497540 | 0.66 | MEN1 (0.47) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL23297291 | 0.66 | POLB (0.53) | TSHRKDM4EPOLBHDAC1 | |
| SCHEMBL23297292 | 0.66 | POLB (0.53) | TSHRKDM4EPOLBHDAC1 | |
| SCHEMBL5497539 | 0.65 | MEN1 (0.54) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL5493680 | 0.62 | TSHR (0.46) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL11144982 | 0.62 | HRH3 (0.54) | MEN1KMT2ATSHRKDM4EMAPT | |
| SCHEMBL5493675 | 0.61 | TSHR (0.56) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL23297358 | 0.61 | MAPT (0.55) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL26363439 | 0.61 | POLB (0.43) | MEN1KMT2ATSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741793-A | PYRIDAZINONE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1998-04-21 | — | — | US | disclosed |