Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1131176 | 1.00 | KDM5A (0.46) | KDM5ACA12CA1CA9PHF8 | |
| Bicarbonate SCHEMBL1132307 | 0.93 | KDM5A (0.47) | KDM5ACA12CA1CA9PHF8 | |
| Bicarbonate SCHEMBL1131246 | 0.93 | KDM5A (0.47) | KDM5ACA12CA1CA9PHF8 | |
| Pyruvate SCHEMBL1132227 | 0.91 | KDM5A (0.43) | KDM5ACA12CA1CA9PHF8 | |
| Acetic Acid SCHEMBL6682749 | 0.91 | KDM5A (0.49) | KDM5APHF8KDM4CALDH1A1LMNA | |
| Oxalic Acid SCHEMBL1131167 | 0.91 | KDM5A (0.46) | KDM5ACA12CA1CA9PHF8 | |
| Oxalic Acid SCHEMBL30185057 | 0.91 | KDM5A (0.46) | KDM5ACA12CA1CA9PHF8 | |
| Acetic Acid SCHEMBL27778890 | 0.91 | CA12 (0.52) | KDM5ACA12CA1CA9PHF8 | |
| Acetic Acid SCHEMBL692128 | 0.91 | CA12 (0.52) | KDM5ACA12CA1CA9PHF8 | |
| Acetic Acid SCHEMBL11801935 | 0.90 | KDM5A (0.47) | KDM5APHF8KDM4CALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11466400-B2 | Finish composition | HEXCEL CORPORATION (US) | 2022-10-11 | — | — | US | claimed |
| EP-3810836-A1 | FINISH COMPOSITION | Hexcel Corporation (US) | 2021-04-28 | — | — | EP | claimed |
| US-4016115-A | Unsaturated polyester resin composition containing titanium dioxide | TOYO BOSEKI KABUSHIKI KAISHA (JA) | 1977-04-05 | — | — | US | claimed |
| US-11466400-B2 | Finish composition | HEXCEL CORPORATION (US) | 2022-10-11 | — | — | US | disclosed |
| EP-3810836-A1 | FINISH COMPOSITION | Hexcel Corporation (US) | 2021-04-28 | — | — | EP | disclosed |
| CN-112313370-A | Finishing agent composition | 赫克赛尔公司 | 2021-02-02 | — | — | CN | disclosed |
| US-5726241-A | Finishing oil for precursor for high performance carbon fibers and precursor | HEXCEL CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |
| US-5571442-A | SILICONE OIL, DICARBOXYLIC ACID MONOESTER EMULSIFIER, AMINOCARBOXYLIC ACID | MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| US-4016115-A | Unsaturated polyester resin composition containing titanium dioxide | TOYO BOSEKI KABUSHIKI KAISHA (JA) | 1977-04-05 | — | — | US | disclosed |