Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867921 | 1.00 | CAPN1 (0.47) | CAPN1CTSKCTSSMEN1GAA | |
| SCHEMBL22994976 | 0.91 | MEN1 (0.51) | CAPN1CTSKCTSSMEN1GAA | |
| SCHEMBL19358763 | 0.91 | MEN1 (0.51) | CAPN1CTSKCTSSMEN1GAA | |
| SCHEMBL19358764 | 0.91 | MEN1 (0.51) | CAPN1CTSKCTSSMEN1GAA | |
| SCHEMBL31725992 | 0.90 | CAPN1 (0.44) | CAPN1CTSKCTSSMEN1GAA | |
| SCHEMBL31407837 | 0.85 | MEN1 (0.56) | CAPN1CTSKCTSSMEN1GAA | |
| SCHEMBL21602732 | 0.85 | MEN1 (0.50) | CAPN1CTSKCTSSMEN1GAA | |
| SCHEMBL29796128 | 0.84 | CAPN1 (0.50) | CAPN1CTSKCTSSMEN1GAA | |
| SCHEMBL20122339 | 0.84 | MEN1 (0.55) | CAPN1CTSKCTSSMEN1GAA | |
| SCHEMBL21176379 | 0.84 | FOLH1 (0.54) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438174-B1 | METHOD FOR INCORPORATING ALIPHATIC AMINO ACIDS COMPRISING ALKYNE, AZIDE OR ALIPHATIC KETONE FUNCTIONAL GROUPS USING APPROPRIATE tRNA/tRNA SYNTHASE PAIRS | MEDICAL RES COUNCIL (GB) | 2018-05-02 | — | — | EP | disclosed |
| US-9868956-B2 | Methods | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-01-16 | — | — | US | disclosed |
| US-20120077948-A1 | Methods | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-03-29 | — | — | US | disclosed |