SCHEMBL8679278

SCHEMBL8679278

Cc1ccc(-c2ccccc2-c2ccccc2)c(C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.52
ELANE P08246 1/20 0.45
PSMB5 P28074 2/20 0.44
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
MAOB P27338 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP2B6 P20813 1/20 0.41
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40
CYP17A1 P05093 1/20 0.39
MAPT P10636 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3285155 0.89 ESR2 (0.63) ESR2ELANEPSMB5LMNASMN1; SMN2
Methylamine SCHEMBL28884788 0.85 ESR2 (0.59) ESR2ELANEPSMB5LMNASMN1; SMN2
SCHEMBL10433952 0.85 ELANE (0.56) ESR2ELANEPSMB5LMNASMN1; SMN2
SCHEMBL11649173 0.83 ESR2 (0.53) ESR2ELANEPSMB5HDAC7ALDH1A1
SCHEMBL7587489 0.83 HDAC7 (0.46) ESR2ELANEPSMB5LMNASMN1; SMN2
SCHEMBL29538733 0.82 BACE1 (0.59) ESR2PSMB5HDAC7CYP2A6CYP2B6
SCHEMBL29590360 0.82 ELANE (0.52) ELANELMNASMN1; SMN2CYP2A6L3MBTL1
SCHEMBL3005820 0.82 ELANE (0.52) ESR2ELANEPSMB5LMNAHDAC7
SCHEMBL11729295 0.82 ELANE (0.52) ELANELMNASMN1; SMN2CYP2A6L3MBTL1
SCHEMBL8056200 0.80 ELANE (0.50) ESR2ELANEPSMB5LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681933-B1 POLYMER-METAL JUNCTION SOLVAY SPECIALTY POLYMERS USA (US) 2024-05-15 EP disclosed
US-11359120-B2 Polymer-metal junction SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-14 US disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed