Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27993791 | 0.83 | MAPT (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17681401 | 0.83 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27740300 | 0.82 | KCNN4 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4022191 | 0.81 | KCNN4 (0.67) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27972690 | 0.79 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7057370 | 0.79 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8166205 | 0.78 | ELANE (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1986527 | 0.77 | CHRM3 (0.46) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL7866041 | 0.77 | CYP1A2 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27264055 | 0.77 | CYP1A2 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1287768-C | Stable oral suspension formulations | PHARMACIA CORP (US) | 2006-12-06 | — | — | CN | disclosed |
| CN-1711081-A | Proline derivatives having affinity for the alpha-2-delta subunit of calcium channels | PFIZER (US) | 2005-12-21 | — | — | CN | disclosed |
| CN-1200696-C | Patch containing anti-inflammatory agent | HISAMITSU PHARMACEUTICAL CO (JP) | 2005-05-11 | — | — | CN | disclosed |
| CN-1549704-A | Stable oral suspension formulations | — | 2004-11-24 | — | — | CN | disclosed |
| US-5728911-A | CATALYTIC SOLUTION COPOLYMERIZATION OF ETHYLENE WITH POLYUNSATURATED MONOMER | DSM COPOLYMER, INC. (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0705284-B1 | PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE | DSM NV (NL) | 1997-07-09 | — | — | EP | disclosed |
| EP-0705284-A1 | PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE | DSM NV (NL) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000564-A1 | PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE | DSM N.V. (NL) | 1995-01-05 | — | — | WO | disclosed |
| EP-0044119-B1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE | STAMICARBON B.V. (NL) | 1985-05-29 | — | — | EP | disclosed |
| US-4435552-A | COORDINATION CATALYST CONTAINING HALOACYL COMPOUND | STAMICARBON B.V. (NL) | 1984-03-06 | — | — | US | disclosed |
| EP-0044119-A2 | Process for the preparation of copolymers of ethylene with at least one other 1-alkene | STAMICARBON B.V. (NL) | 1982-01-20 | — | — | EP | disclosed |