SCHEMBL8680231

SCHEMBL8680231

CCCCCCCCC(CCCCCCCC(=O)O)C(=O)OCCOCCOCCOC(=O)C(CCCCCCCC)CCCCCCCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.56
FFAR1 O14842 2/20 0.56
GPR84 Q9NQS5 7/20 0.53
PPARG P37231 7/20 0.53
PPARD Q03181 7/20 0.53
PPARA Q07869 7/20 0.53
HDAC11 Q96DB2 5/20 0.53
TSHR P16473 4/20 0.53
PTPN1 P18031 3/20 0.53
ALDH1A1 P00352 3/20 0.53
TLR2 O60603 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
FABP4 P15090 2/20 0.53
KMT2A Q03164 2/20 0.53
SLC22A6 Q4U2R8 1/20 0.53
SLC22A8 Q8TCC7 1/20 0.53
MEN1 O00255 1/20 0.53
ESR1 P03372 1/20 0.53
ALOX15 P16050 1/20 0.53
PDE4A P27815 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5697735 1.00 FFAR4 (0.56) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL8027209 1.00 FFAR4 (0.56) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL7627080 0.94 FFAR4 (0.50) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL887853 0.94 FFAR4 (0.50) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL2138337 0.94 FFAR4 (0.50) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL2141516 0.93 FFAR4 (0.47) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL23532301 0.90 FFAR4 (0.59) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL2921584 0.90 FFAR4 (0.59) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL18148741 0.90 FFAR4 (0.59) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL300422 0.90 FFAR4 (0.59) FFAR4FFAR1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470040-B1 Process for the preparation of a rubber having polymer bound functionality GOODYEAR TIRE & RUBBER (US) 1996-09-11 EP claimed
EP-0470042-B1 Process for the preparation of a masterbatch rubber having polymer bound functionality GOODYEAR TIRE & RUBBER (US) 1996-05-08 EP claimed
US-5284907-A Emulsion polymerization of an unsaturated compound having a moiety of a rubber additive and a conjugated diene using an ionic surfactant and a plasticizer functioning as the solvent and dispersant THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-02-08 US claimed
US-5284906-A Process for the preparation of a rubber having polymer bound functionality THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-02-08 US claimed
EP-0470040-A1 Process for the preparation of a rubber having polymer bound functionality THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-02-05 EP claimed
EP-0470042-A1 Process for the preparation of a masterbatch rubber having polymer bound functionality THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-02-05 EP claimed
US-5840801-A VULCANIZATION OF ELASTOMERS, ZINC OXIDE, BLOCK COPOLYMERS ARIZONA CHEMICAL COMPANY (US) 1998-11-24 US disclosed
WO-1997049763-A1 METHOD FOR IMPROVING DISPERSION AND COMPATIBILITY OF ZINC SALTS IN ELASTOMERIC COMPOUNDS DURING VULCANIZATION ARIZONA CHEMICAL COMPANY (US) 1997-12-31 WO disclosed
EP-0470040-B1 Process for the preparation of a rubber having polymer bound functionality GOODYEAR TIRE & RUBBER (US) 1996-09-11 EP disclosed
EP-0470042-B1 Process for the preparation of a masterbatch rubber having polymer bound functionality GOODYEAR TIRE & RUBBER (US) 1996-05-08 EP disclosed
US-5284907-A Emulsion polymerization of an unsaturated compound having a moiety of a rubber additive and a conjugated diene using an ionic surfactant and a plasticizer functioning as the solvent and dispersant THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-02-08 US disclosed
US-5284906-A Process for the preparation of a rubber having polymer bound functionality THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-02-08 US disclosed
EP-0470040-A1 Process for the preparation of a rubber having polymer bound functionality THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-02-05 EP disclosed
EP-0470042-A1 Process for the preparation of a masterbatch rubber having polymer bound functionality THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-02-05 EP disclosed