Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033645 | 0.96 | ESR1 (0.42) | ESR1ESR2PTGS1PTGS2SLC6A2 | |
| SCHEMBL5679013 | 0.87 | ESR1 (0.44) | ESR1ESR2PTGS1PTGS2SLC6A2 | |
| SCHEMBL18888810 | 0.85 | ESR1 (0.55) | ESR1ESR2PTGS1PTGS2SLC6A2 | |
| SCHEMBL23854324 | 0.84 | CA1 (0.42) | ESR1ESR2PTGS1PTGS2PGR | |
| SCHEMBL14995300 | 0.84 | ESR1 (0.48) | ESR1ESR2PTGS1SLC6A2LMNA | |
| SCHEMBL4649854 | 0.84 | ESR1 (0.67) | ESR1ESR2PTGS1PTGS2SLC6A2 | |
| SCHEMBL28221017 | 0.84 | PTGS1 (0.42) | PTGS1PTGS2SLC6A2LMNACYP1A2 | |
| SCHEMBL8351878 | 0.82 | ESR1 (0.48) | ESR1ESR2PTGS1PTGS2PGR | |
| SCHEMBL8357018 | 0.82 | ESR1 (0.53) | ESR1ESR2PTGS2SLC6A2LMNA | |
| SCHEMBL4025450 | 0.80 | ESR1 (0.50) | ESR1ESR2PTGS2SLC6A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853949-A | Method of synthesizing polyphenol compound and positive working photoresist composition comprising polyphenol compound | FUJI PHOTO FILM CO., LTD. (JP) | 1998-12-29 | — | — | US | disclosed |