Ethylene Glycol

Ethylene Glycol

SCHEMBL8680442

O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.OCCO

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.60
HSD17B10 Q99714 2/20 0.57
CDC25A P30304 1/20 0.57
CDC25B P30305 1/20 0.57
POLB P06746 4/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
ACE2 Q9BYF1 2/20 0.46
TSHR P16473 3/20 0.46
TP53 P04637 1/20 0.46
MYC P01106 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
PTGS2 P35354 1/20 0.45
CA7 P43166 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3621691 1.00 KDM4E (0.60) KDM4EHSD17B10CDC25ACDC25BPOLB
Ethylene Glycol SCHEMBL29410653 1.00 KDM4E (0.60) KDM4EHSD17B10CDC25ACDC25BPOLB
Ethylene Glycol SCHEMBL3107860 1.00 KDM4E (0.60) KDM4EHSD17B10CDC25ACDC25BPOLB
Ethylene Glycol SCHEMBL29027475 1.00 KDM4E (0.60) KDM4EHSD17B10CDC25ACDC25BPOLB
Ethylene Glycol SCHEMBL31229853 0.98 KDM4E (0.58) KDM4EHSD17B10CDC25ACDC25BPOLB
Ethylene Glycol SCHEMBL27473334 0.98 KDM4E (0.58) KDM4EHSD17B10CDC25ACDC25BPOLB
Terephthalic Acid SCHEMBL5695219 0.98 KDM4E (0.58) KDM4EHSD17B10CDC25ACDC25BPOLB
Isophthalic Acid SCHEMBL7528600 0.92 KDM4E (0.62) KDM4EHSD17B10CDC25ACDC25BPOLB
1,6-Hexanediol SCHEMBL28253995 0.92 KDM4E (0.53) KDM4EHSD17B10CDC25ACDC25BPOLB
1,4-Butanediol SCHEMBL29185198 0.92 KDM4E (0.56) KDM4EHSD17B10CDC25ACDC25BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845486-A1 EPOXIDIZED POLYENE, EPOXY RESIN COMPOSITION AND PRODUCT OF CURING THEREOF, AND POWDER COATING MATERIAL DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-03 EP disclosed