SCHEMBL8680528

SCHEMBL8680528

CN1c2ccccc2C(C)(C)C12C=Cc1ccc(Cl)c([N+](=O)[O-])c1O2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.49
LMNA P02545 5/20 0.49
GAA P10253 4/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
NPSR1 Q6W5P4 3/20 0.49
RECQL P46063 3/20 0.49
TDP1 Q9NUW8 3/20 0.49
ALOX15 P16050 2/20 0.49
ALPG P10696 1/20 0.49
TP53 P04637 1/20 0.49
HSD17B10 Q99714 1/20 0.49
GFER P55789 1/20 0.43
SMN1; SMN2 Q16637 5/20 0.35
THRB P10828 5/20 0.35
PKM P14618 2/20 0.35
PLIN1 O60240 1/20 0.35
TSHR P16473 1/20 0.35
PLIN5 Q00G26 1/20 0.35
ABHD5 Q8WTS1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8681206 0.84 MAPT (0.55) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8680948 0.83 MAPT (0.52) MAPTLMNAGAAMEN1KMT2A
SCHEMBL608699 0.81 MAPT (0.53) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8680072 0.81 MAPT (0.50) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8679983 0.81 MAPT (0.44) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8680655 0.81 MAPT (0.52) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8680325 0.81 MAPT (0.56) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8680366 0.80 MAPT (0.51) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8685189 0.80 MAPT (0.43) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8680583 0.79 MAPT (0.50) MAPTLMNAGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed