Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886689 | 1.00 | TSHR (0.48) | TSHRFAAHTRPV1HIF1AADH1B | |
| SCHEMBL6744017 | 1.00 | TSHR (0.48) | TSHRFAAHTRPV1HIF1AADH1B | |
| SCHEMBL29170278 | 1.00 | TSHR (0.48) | TSHRFAAHTRPV1HIF1AADH1B | |
| SCHEMBL4433196 | 1.00 | TSHR (0.48) | TSHRFAAHTRPV1HIF1AADH1B | |
| SCHEMBL29150311 | 1.00 | TSHR (0.48) | TSHRFAAHTRPV1HIF1AADH1B | |
| SCHEMBL10522037 | 0.98 | TSHR (0.44) | TSHRFAAHTRPV1HIF1AADH1B | |
| Palmitaldehyde SCHEMBL10437527 | 0.92 | TSHR (0.64) | TSHRFAAHTRPV1ADH1BADH1C | |
| Undecanal SCHEMBL5388011 | 0.92 | TSHR (0.64) | TSHRFAAHTRPV1ADH1BADH1C | |
| Tetradecanal SCHEMBL6162330 | 0.92 | TSHR (0.64) | TSHRFAAHTRPV1ADH1BADH1C | |
| Dodecanal SCHEMBL14331913 | 0.92 | TSHR (0.64) | TSHRFAAHTRPV1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744649-A | CATALYSTS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-04-28 | — | — | US | disclosed |
| US-5744650-A | USING METAL-ORGANOPOLYPHOSPHITE LIGAND COMPLEX CATALYST AND CONTROLLING CARBON MONOXIDE PARTIAL PRESSURE AND TEMPERATURE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-04-28 | — | — | US | disclosed |