Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10173246 | 0.92 | HDAC1 (0.48) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL842287 | 0.92 | HDAC1 (0.51) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL3369119 | 0.78 | HDAC1 (0.50) | HDAC1HDAC8 | |
| SCHEMBL8243542 | 0.71 | KMT2A (0.33) | — | |
| SCHEMBL833990 | 0.71 | HDAC1 (0.62) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL833989 | 0.71 | HDAC1 (0.62) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL12560623 | 0.70 | HDAC1 (0.63) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL833378 | 0.69 | HDAC1 (0.77) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL830716 | 0.69 | HDAC1 (0.77) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL833379 | 0.69 | HDAC1 (0.77) | HDAC1HDAC8HDAC3HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143282-B2 | Heterocyclic compounds | S*BIO PTE LTD. (SG) | 2012-03-27 | — | — | US | disclosed |