Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10860757 | 0.95 | SPHK1 (0.44) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL9064879 | 0.89 | SPHK1 (0.62) | SPHK1SPHK2ALDH1A1LMNA | |
| SCHEMBL14190727 | 0.86 | SPHK1 (0.47) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL4323763 | 0.84 | SPHK1 (0.61) | SPHK1SPHK2 | |
| SCHEMBL10816245 | 0.84 | CYP2C9 (0.43) | SPHK1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9346694 | 0.83 | SPHK1 (0.53) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL12736282 | 0.83 | EP300 (0.38) | SPHK1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL11466853 | 0.81 | CYP2C9 (0.58) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL10486078 | 0.81 | CYP2C9 (0.58) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL11466923 | 0.81 | CYP2C9 (0.58) | SPHK1SPHK2CYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58134046-A | — | — | None | — | — | JP | disclosed |
| US-5779936-A | FLUORINATED BICYCLOHEXANE OR CYCLOHEXYLETHYL CYCLOHEXANE DERIVATIVE HAVING LOW VISCOSITY AND HIGH CLEARING POINT TEMPERATURE | CHISSO CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0742275-A1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1996-11-13 | — | — | EP | disclosed |
| JP-S58134046-A | TRNS-4-ALKYLOXYMETHYL-1-(4'-ALKYLBIPHENYLYL-4-CYCLOEXANES | CHISSO CORP | 1983-08-10 | — | — | JP | disclosed |