SCHEMBL8681

SCHEMBL8681

CC([O])F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL868390 1.00
SCHEMBL868486 1.00
SCHEMBL4951236 0.78
SCHEMBL20474611 0.78
SCHEMBL868179 0.78
SCHEMBL477906 0.78
SCHEMBL8355029 0.78
SCHEMBL126483 0.78
SCHEMBL7858165 0.78
SCHEMBL29029 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7652 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894404-B Small molecular compound with naphthylamine structure and application thereof 杭州天玑济世生物科技有限公司 2024-07-16 CN claimed
WO-2024125668-A1 HETEROCYCLIC SUBSTITUTED PENTA-SIX-MEMBERED HETEROARYL DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION AND PREPARATION METHOD THEREFOR 上海海雁医药科技有限公司 2024-06-20 WO claimed
CN-112469710-B Pyridyl and pyrazinyl- (aza) indole sulfonamides 优时比制药有限公司 2024-05-14 CN claimed
WO-2024095003-A1 NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY Cerevance, Inc. (US) 2024-05-10 WO claimed
WO-2024095005-A1 DIARYL DIAZOLE AND DIARYL TRIAZOLE DERIVATIVES FOR USE IN TREATING A DISEASE ASSOCIATED WITH KCNK13 ACTIVITY Cerevance, Inc. (US) 2024-05-10 WO claimed
CN-117957215-A Small molecular compound with naphthylamine structure and application thereof 杭州天玑济世生物科技有限公司 2024-04-30 CN claimed
US-11939319-B2 Pyridinyl and pyrazinyl-(asa)indolsulfonamides UCB PHARMA GMBH (DE) 2024-03-26 US claimed
CN-117477028-A Overcharge-preventing core and application thereof 华电内蒙古能源有限公司 2024-01-30 CN claimed
CN-117327000-A Biphenyl tetrahydropyrrole compound and preparation method and application thereof 海南因瑞生物医药科技有限公司 2024-01-02 CN claimed
US-20230391758-A1 MODIFIED BENZOFURAN-CARBOXAMIDES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS MERCK SHARP & DOHME LLC (US) 2023-12-07 US claimed
US-5610121-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-11 US claimed
US-5382644-A Linear polyphosphazenes and a process for their production CARNEGIE MELLON UNIVERSITY (US) 1995-01-17 US claimed
EP-0280240-B1 Cephalosporin derivatives, process for their preparation and antibacterial agents BANYU PHARMA CO LTD (JP) 1994-09-14 EP claimed
US-5100458-A Pyrimidine substituted, plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1992-03-31 US claimed
US-4950666-A INSECTS, ACARIDS, AND NEMATODES FMC CORPORATION (US) 1990-08-21 US claimed
EP-0370704-A2 Aralkylamine derivatives, preparation thereof and fungicides containing the same UBE INDUSTRIES, LTD. (JP) 1990-05-30 EP claimed
EP-0232538-B1 5-ACYLAMIDO-1-ARYL PYRAZOLES BAYER AG (DE) 1990-05-23 EP claimed
EP-0349283-A1 Novel herbicidal 2-sulfonyliminothiazolidines ZENECA INC. (US) 1990-01-03 EP claimed
EP-0132680-B1 SUBSTITUTED FURAZANS BAYER AG (DE) 1987-01-28 EP claimed
EP-0129153-B1 1-ACETONYL-2-(PHENYLIMINO)-IMIDAZOLIDINES, THEIR ADDITION SALTS, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR PREPARATION BOEHRINGER INGELHEIM KG (DE) 1986-11-20 EP claimed