Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682986 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1SSTR4SMN1; SMN2PTGDR2 | |
| SCHEMBL8681757 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1SSTR4SMN1; SMN2PTGDR2 | |
| SCHEMBL8686869 | 0.98 | KDM4E (0.43) | KDM4EALDH1A1SSTR4SMN1; SMN2PTGDR2 | |
| SCHEMBL2717711 | 0.86 | MCHR1 (0.47) | SSTR4PPARGPPARAMCHR1 | |
| SCHEMBL15850421 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2HPGDPPARG | |
| SCHEMBL22229831 | 0.84 | PTGDR2 (0.51) | PTGDR2PPARGPPARA | |
| SCHEMBL8682989 | 0.83 | PPARG (0.45) | KDM4EALDH1A1PTGDR2PPARGPPARA | |
| SCHEMBL8686864 | 0.83 | PPARG (0.45) | KDM4EALDH1A1PTGDR2PPARGPPARA | |
| SCHEMBL8681866 | 0.83 | PPARG (0.45) | KDM4EALDH1A1PTGDR2PPARGPPARA | |
| SCHEMBL8681710 | 0.82 | MCHR1 (0.40) | KDM4EALDH1A1PTGDR2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780194-A | PHOTOSENSITIVE LAYER OF POLYESTER BINDING RESIN, ELECTRIC CHARGE GENERATING MATERIAL, AND HOLE TRANSFERRING MATERIAL | MITA INDUSTRIAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |