⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580578 | 1.00 | — | — | |
| SCHEMBL3807866 | 1.00 | — | — | |
| SCHEMBL13084109 | 1.00 | — | — | |
| SCHEMBL13497245 | 1.00 | — | — | |
| SCHEMBL2802666 | 1.00 | — | — | |
| SCHEMBL24943522 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL6933813 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL18850030 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL22045699 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL21370154 | 0.85 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121328-A1 | METHODS AND COMPOSITIONS FOR REDUCING BODY WEIGHT AND INCREASING GUT MOTILITY | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2017-07-20 | — | — | WO | disclosed |
| US-8383609-B2 | Phosphorus containing heterocyclic compounds, sugar analogues, and compositions having anti-cancer activity containing the same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-02-26 | — | — | US | disclosed |
| US-8212011-B2 | Novobiocin analogues | UNIVERSITY OF KANSAS (US) | 2012-07-03 | — | — | US | disclosed |
| US-20100298272-A1 | PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-11-25 | — | — | US | disclosed |
| US-7622451-B2 | Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders | UNIVERSITY OF KANSAS (US) | 2009-11-24 | — | — | US | disclosed |
| US-7608594-B2 | Novobiocin analogues as anticancer agents | UNIVERSITY OF KANSAS (US) | 2009-10-27 | — | — | US | disclosed |
| US-20090187014-A1 | Novobiocin Analogues | UNIVERSITY OF KANSAS | 2009-07-23 | — | — | US | disclosed |
| WO-1998000564-A1 | METHODS AND COMPOSITIONS FOR SEQUENCE-SPECIFIC HYBRIDIZATION OF RNA BY 2'-5' OLIGONUCLEOTIDES | DYAD PHARMACEUTICAL CORPORATION (US) | 1998-01-08 | — | — | WO | disclosed |