Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 18/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684391 | 1.00 | FDFT1 (0.68) | FDFT1 | |
| SCHEMBL8684396 | 1.00 | FDFT1 (0.68) | FDFT1 | |
| SCHEMBL6953607 | 0.90 | FDFT1 (0.75) | FDFT1 | |
| SCHEMBL6953603 | 0.90 | FDFT1 (0.75) | FDFT1 | |
| SCHEMBL6953604 | 0.90 | FDFT1 (0.75) | FDFT1 | |
| SCHEMBL8689429 | 0.89 | FDFT1 (0.57) | FDFT1 | |
| SCHEMBL8689431 | 0.89 | FDFT1 (0.57) | FDFT1 | |
| SCHEMBL8689423 | 0.89 | FDFT1 (0.57) | FDFT1 | |
| SCHEMBL8685827 | 0.89 | FDFT1 (0.59) | FDFT1 | |
| SCHEMBL8685831 | 0.89 | FDFT1 (0.59) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770594-A | ANTICHOLESTEROL AGENTS, INHIBITORS OF CHOLESTEROL SYNTHESIS | PFIZER INC. (US) | 1998-06-23 | — | — | US | claimed |
| WO-1996020184-A1 | NAPHTHYL-BENZOXAZEPINES OR -BENZOTHIAZEPINES AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1996-07-04 | — | — | WO | claimed |
| US-5770594-A | ANTICHOLESTEROL AGENTS, INHIBITORS OF CHOLESTEROL SYNTHESIS | PFIZER INC. (US) | 1998-06-23 | — | — | US | disclosed |
| WO-1996020184-A1 | NAPHTHYL-BENZOXAZEPINES OR -BENZOTHIAZEPINES AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1996-07-04 | — | — | WO | disclosed |