SCHEMBL868458

SCHEMBL868458

CCCCCCCCCOC(=O)C(C)=Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.53
LMNA P02545 4/20 0.53
ALDH1A1 P00352 3/20 0.53
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPK1 P28482 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 2/20 0.49
AKR1C3 P42330 1/20 0.49
KDM4E B2RXH2 3/20 0.48
POLB P06746 1/20 0.47
HSD17B10 Q99714 1/20 0.47
PPARG P37231 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
PLA2G4A P47712 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27769186 1.00 TSHR (0.53) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL27956127 1.00 TSHR (0.53) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL27345528 1.00 TSHR (0.53) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL5174859 1.00 TSHR (0.53) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL8702266 0.94 KDM4E (0.53) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL2532167 0.94 KDM4E (0.53) TSHRLMNAALDH1A1TP53CYP3A4
Methacrylic Acid SCHEMBL28957420 0.92 TSHR (0.51) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL1683262 0.88 MEN1 (0.56) TSHRLMNAALDH1A1MAPK1MEN1
SCHEMBL7771764 0.87 TSHR (0.54) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL10898416 0.86 KMT2A (0.59) TSHRLMNAALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103189430-A Preparation of foam materials derived from renewable resources PROCTER & GAMBLE 2013-07-03 CN claimed
CN-1454224-A Branched/block capolymers for treatment of keratinous substrates NOVEON IP HOLDINGS CORP (US) 2003-11-05 CN claimed
CN-1041770-A WATER-DISPERSIBLE HYDROPHOBIC THICKENER AMERICAN CYANAMID CO (US) 1990-05-02 CN claimed
US-20220220031-A1 GRANULATE MATERIAL AND ASSOCIATED COATING THAT IS LOW IN ODOR AND EMISSIONS, PARTICULARLY A CONSTRUCTION ELEMENT COATING, FOR EXAMPLE A FLOOR COATING, BASED ON A RADICAL POLYMERIZATION SIDEC NV (BE) 2022-07-14 US disclosed
CN-112220158-B Cold-bonding waterproof shoe and processing technology thereof 温州程泓鞋业有限公司 2021-09-10 CN disclosed
CN-112220158-A Cold-bonding waterproof shoe and processing technology thereof 温州程泓鞋业有限公司 2021-01-15 CN disclosed
WO-2020239877-A1 GRANULATE MATERIAL AND ASSOCIATED COATING THAT IS LOW IN ODOR AND EMISSIONS, PARTICULARLY A CONSTRUCTION ELEMENT COATING, FOR EXAMPLE A FLOOR COATING, BASED ON A RADICAL POLYMERIZATION SIDEC NV (BE) 2020-12-03 WO disclosed
CN-109789078-A Resin binder composition based on (methyl) acrylate 赢创有限公司 2019-05-21 CN disclosed
CN-109689815-A Thermohardening type electrically conductive adhesive 三键有限公司 2019-04-26 CN disclosed
CN-109215847-A Transparent and electrically conductive film and touch panel 日东电工株式会社 2019-01-15 CN disclosed
CN-105007884-B Polymers and methods for mitigating loss of silicone deposition on keratinous substrates 路博润先进材料公司 2018-09-28 CN disclosed
CN-1282036-C Resist curable resin composition and cured article thereof SHOWA DENKO KK (JP) 2006-10-25 CN disclosed
CN-1697861-A Pigment dispersion and ink composition and ink set both containing the same SEIKO EPSON CORP (JP) 2005-11-16 CN disclosed
CN-1589182-A Method for producing layers ROEHM GMBH (DE) 2005-03-02 CN disclosed
CN-1464996-A resist curable resin composition and cured product thereof SHOWA DENKO KK (JP) 2003-12-31 CN disclosed
CN-1454224-A Branched/block capolymers for treatment of keratinous substrates NOVEON IP HOLDINGS CORP (US) 2003-11-05 CN disclosed
CN-1392971-A Photosensitive composition, cured article thereof, and printed circuit board using same SHOWA DENKO KK (JP) 2003-01-22 CN disclosed
US-5292610-A Containing leuco dye, photopolymerization initiator and photopolymerizable monomer AGFA GEVAERT AG (DE) 1994-03-08 US disclosed
US-5266549-A Aromatic vinyl-nitrile-acrylate interpolymer AGFA-GEVAERT AKTIENGESELLSCHAFT 1993-11-30 US disclosed
CN-1041770-A WATER-DISPERSIBLE HYDROPHOBIC THICKENER AMERICAN CYANAMID CO (US) 1990-05-02 CN disclosed