Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 2/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 2/20 | 1.00 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.65 |
| ▸ | SHBG | P04278 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.65 |
| ▸ | AR | P10275 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | MGAM | O43451 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891363 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL1114187 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL15369324 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL12394882 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL16305624 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL12377165 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL868472 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL15426613 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL22844489 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL1331733 | 1.00 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933624-B | Artificial synthesis method of natural product (+) -digitonin | 大连理工大学 | 2024-02-20 | — | — | CN | claimed |
| CN-114933624-A | Method for artificially synthesizing natural product (+) -digitoxin aglycone | 大连理工大学 | 2022-08-23 | — | — | CN | claimed |
| EP-2279195-B1 | MEDICINAL APPLICATIONS OF BENZOIC ACID HYDRAZONES SYNTHESIZED ON THE BASIS OF STEROIDAL TIGOGENIN | SHELAR ASHOK RANGANATH (IN) | 2013-05-15 | — | — | EP | claimed |
| WO-2011063774-A2 | PECTIN COMPLEXES OF STEROIDS AND PHARMACEUTICAL COMPOSITIONS BASED THEREON | ZENTIVA, K.S. (CZ) | 2011-06-03 | — | — | WO | claimed |
| EP-1962856-B1 | MEDICAMENT BASED ON A MONOESTER OF STEROIDS WITH LONG CHAIN FATTY ACIDS | PETRONI ANNA (IT) | 2010-10-20 | — | — | EP | claimed |
| EP-1807062-A4 | USE OF ANDROGENS TO REDUCE THE LIKELIHOOD OF ACQUIRING OR TO TREAT SKIN AGING | ENDORECH INC (CA) | 2009-06-03 | — | — | EP | claimed |
| EP-1962856-A2 | MEDICAMENT BASED ON A MONOESTER OF STEROIDS WITH LONG CHAIN FATTY ACIDS | Petroni, Anna (IT) | 2008-09-03 | — | — | EP | claimed |
| EP-1807062-A1 | USE OF ANDROGENS TO REDUCE THE LIKELIHOOD OF ACQUIRING OR TO TREAT SKIN AGING | Endorecherche Inc. (CA) | 2007-07-18 | — | — | EP | claimed |
| WO-2007068434-A2 | MEDICAMENT BASED ON A MONOESTER OF STEROIDS WITH LONG CHAIN FATTY ACIDS | PETRONI ANNA (IT) | 2007-06-21 | — | — | WO | claimed |
| WO-2006047859-A1 | USE OF ANDROGENS TO REDUCE THE LIKELIHOOD OF ACQUIRING OR TO TREAT SKIN AGING | ENDORECHERCHE, INC. (CA) | 2006-05-11 | — | — | WO | claimed |
| EP-0801557-B1 | LIPOSOME FORMULATIONS OF 5BETA STEROIDS | SUPERGEN INC (US) | 2003-07-02 | — | — | EP | claimed |
| US-6333317-B1 | Regulation of amyloid precursor protein (APP) expression by administration of an estrogenic compound | MASSACHUSETTES INSTITUTE OF TECHNOLOGY | 2001-12-25 | — | — | US | claimed |
| EP-0269786-B1 | Quantitative analysis of 3-oxo-5Beta-Steroid and reagent therefor | DAIICHI PURE CHEMICALS CO LTD (JP) | 1993-11-03 | — | — | EP | claimed |
| US-5085989-A | Contacting sample with specific dehydrogenase and tetrazolium salt, measuring optical density of colored substance produced; diagnosis of liver disorders | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 1992-02-04 | — | — | US | claimed |
| EP-0160434-A1 | Manufacture of androstandione | Progenics, Inc. (US) | 1985-11-06 | — | — | EP | claimed |
| US-4097334-A | Process for the preparation of androstane-3,17-dione derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | claimed |
| WO-2024092274-A2 | ENDOCYTIC AGENTS | BIOVENTURES, LLC (US) | 2024-05-02 | — | — | WO | disclosed |
| CN-114933624-B | Artificial synthesis method of natural product (+) -digitonin | 大连理工大学 | 2024-02-20 | — | — | CN | disclosed |
| US-4097334-A | Process for the preparation of androstane-3,17-dione derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |
| US-4097334-A | Process for the preparation of androstane-3,17-dione derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |