SCHEMBL8685192

SCHEMBL8685192

CN1c2ccccc2C=CC12C=Cc1ccccc1O2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
MAPT P10636 6/20 0.39
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
NPSR1 Q6W5P4 4/20 0.39
GAA P10253 4/20 0.39
LMNA P02545 4/20 0.39
TP53 P04637 3/20 0.39
RECQL P46063 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
ALPG P10696 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 2/20 0.37
MAPK1 P28482 1/20 0.37
UBE2N P61088 1/20 0.37
HTT P42858 1/20 0.35
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8680171 0.84 NPSR1 (0.46) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL8680359 0.82 HTR2C (0.47) HTR2CMAPTMEN1KMT2ANPSR1
SCHEMBL8684880 0.82 MAPT (0.52) HTR2CMAPTMEN1KMT2ANPSR1
SCHEMBL8688282 0.80 MEN1 (0.47) MAPTMEN1KMT2ANPSR1GAA
SCHEMBL8682725 0.80 NPSR1 (0.39) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL8680311 0.79 SMN1; SMN2 (0.44) MAPTMEN1KMT2ANPSR1GAA
SCHEMBL8680097 0.74 HTR2C (0.39) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL8862518 0.71 MAPT (0.40) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL29466134 0.71 MAPT (0.73) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL29783017 0.71 MAPT (0.73) HTR2CHTR2BMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed