Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | POLQ | O75417 | 6/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685628 | 0.81 | DAO (0.41) | DAOKIF11LMNAPOLBMAPT | |
| SCHEMBL7489457 | 0.76 | AHR (0.49) | DAOKIF11POLQ | |
| SCHEMBL8685738 | 0.74 | CYP2A6 (0.40) | KIF11PIM1PIM3EGFR | |
| SCHEMBL18586027 | 0.73 | PARP1 (0.48) | DAOKIF11PIM1PIM3KDM4E | |
| SCHEMBL8685272 | 0.70 | GCGR (0.42) | DAOPOLQLMNA | |
| SCHEMBL18586039 | 0.70 | PARP1 (0.43) | DAOKIF11PIM1PIM3KDM4E | |
| SCHEMBL18586827 | 0.70 | PARP1 (0.45) | DAOKIF11KDM4E | |
| SCHEMBL18586826 | 0.67 | HRH3 (0.44) | PIM1PIM3KDM4E | |
| SCHEMBL8685220 | 0.67 | AKR1B1 (0.43) | KIF11MAPT | |
| SCHEMBL2648755 | 0.66 | KDM4E (0.41) | EGFRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |