Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688268 | 1.00 | SPHK1 (0.57) | SPHK1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL8685810 | 1.00 | SPHK1 (0.57) | SPHK1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL8686872 | 1.00 | SPHK1 (0.57) | SPHK1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL8686851 | 1.00 | SPHK1 (0.57) | SPHK1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL8686091 | 1.00 | SPHK1 (0.57) | SPHK1OPRM1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL6912434 | 0.98 | SPHK1 (0.55) | SPHK1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL6730336 | 0.98 | SPHK1 (0.54) | SPHK1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL15469804 | 0.91 | SPHK1 (0.45) | SPHK1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL8685957 | 0.89 | SPHK1 (0.47) | SPHK1S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL3676653 | 0.84 | SPHK1 (0.54) | SPHK1OPRM1S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529528-A | Reacting an alkoxylated amine and a phosphite | MOBIL OIL CORPORATION (US) | 1985-07-16 | — | — | US | claimed |
| US-5824626-A | Process for preparing trithianes and phosphorus acid and/or thiophosphorus acid derivatives | THE LUBRIZOL CORPORATION (US) | 1998-10-20 | — | — | US | disclosed |
| EP-0522133-B1 | TRITHIANES AND PHOSPHORUS ACID AND/OR THIOPHOSPHORUS ACID DERIVATIVES | LUBRIZOL CORP (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5194166-A | Phosphorous amine lubricant additives | THE ELCO CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| US-5182037-A | PHOSPHORUS- AND/OR NITROGEN-CONTAINING DERIVATIVES OF SULFUR-CONTAINING COMPOUNDS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0522133-A1 | TRITHIANES AND PHOSPHORUS ACID AND/OR THIOPHOSPHORUS ACID DERIVATIVES. | LUBRIZOL CORP (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0318511-B1 | BORATED AMINE SALTS OF MONOTHIOPHOSPHORIC ACIDS | The Lubrizol Corporation (US) | 1992-09-23 | — | — | EP | disclosed |
| WO-1992012225-A1 | TRITHIANES AND PHOSPHORUS ACID AND/OR THIOPHOSPHORUS ACID DERIVATIVES | THE LUBRIZOL CORPORATION (US) | 1992-07-23 | — | — | WO | disclosed |
| US-5130036-A | Friction reducing phosphorous alkoxylated amine lubricants | THE ELCO CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0289592-B1 | PHOSPHORUS- AND/OR NITROGEN-CONTAINING DERIVATIVES IN LUBRICANT COMPOSITIONS | The Lubrizol Corporation (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0325977-B1 | PHOSPHITE AMINE LUBRICANT ADDITIVES | THE ELCO CORPORATION (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0456888-A1 | Phosphorous amine lubricant additives | THE ELCO CORPORATION (US) | 1991-11-21 | — | — | EP | disclosed |
| US-4992184-A | Reaction product of arylsulfonic acid and (diol or amine) phosphite | MOBIL OIL CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4965002-A | Reaction product of alkoxylated amine and organic phosphize | ELCO CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0325977-A1 | Phosphite amine lubricant additives | THE ELCO CORPORATION (US) | 1989-08-02 | — | — | EP | disclosed |
| EP-0309486-A1 | PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS | The Lubrizol Corporation (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4755311-A | Borated amine salt of dihydrocarbyl monothiophosphoric acid | THE LUBRIZOL CORPORATION (US) | 1988-07-05 | — | — | US | disclosed |
| WO-1987007638-A2 | PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 1987-12-17 | — | — | WO | disclosed |
| US-4557845-A | FRICTION REDUCERS AND FUEL CONSUMPTION REDUCERS | MOBIL OIL CORPORATION (US) | 1985-12-10 | — | — | US | disclosed |
| US-4529528-A | Reacting an alkoxylated amine and a phosphite | MOBIL OIL CORPORATION (US) | 1985-07-16 | — | — | US | disclosed |