Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685554 | 0.90 | PIM1 (0.50) | PIM1GSK3AGSK3BTSHRHTR6 | |
| SCHEMBL8690628 | 0.90 | PIM1 (0.52) | PIM1GSK3AGSK3BTSHRHTR6 | |
| SCHEMBL8685413 | 0.90 | GSK3A (0.49) | PIM1GSK3AGSK3BTSHRHTR6 | |
| SCHEMBL8684847 | 0.89 | PIM1 (0.51) | PIM1GSK3AGSK3BHTR6ALDH1A1 | |
| SCHEMBL8686360 | 0.89 | GSK3A (0.48) | PIM1GSK3AGSK3BHTR6POLB | |
| SCHEMBL8685098 | 0.89 | GSK3A (0.48) | PIM1GSK3AGSK3BHTR6POLB | |
| SCHEMBL8686780 | 0.89 | GSK3A (0.48) | PIM1GSK3AGSK3BTSHRHTR6 | |
| SCHEMBL8685354 | 0.88 | PIM1 (0.53) | PIM1GSK3AGSK3BTSHRHTR6 | |
| SCHEMBL8685620 | 0.86 | GSK3A (0.50) | PIM1GSK3AGSK3BHTR6POLB | |
| SCHEMBL8685916 | 0.86 | PIM1 (0.56) | PIM1GSK3AGSK3BTSHRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |