Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SCN4A | P35499 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8687746 | 0.98 | S1PR5 (0.53) | S1PR5ALDH1A1SCN4AMEN1TSHR | |
| SCHEMBL5501378 | 0.90 | KMT2A (0.57) | ALDH1A1MEN1TSHRKMT2AACHE | |
| SCHEMBL19385016 | 0.84 | S1PR5 (0.54) | S1PR5ALDH1A1SCN4AMEN1TSHR | |
| SCHEMBL2450749 | 0.84 | GAA (0.63) | S1PR5ALDH1A1SCN4AMEN1TSHR | |
| SCHEMBL6286609 | 0.84 | GAA (0.63) | S1PR5ALDH1A1SCN4AMEN1TSHR | |
| SCHEMBL6284121 | 0.84 | GAA (0.63) | S1PR5ALDH1A1SCN4AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL19385069 | 0.83 | S1PR5 (0.53) | S1PR5ALDH1A1SCN4AMEN1TSHR | |
| SCHEMBL12716627 | 0.82 | S1PR5 (0.58) | S1PR5ALDH1A1SCN4AMEN1TSHR | |
| SCHEMBL250506 | 0.81 | S1PR5 (0.77) | S1PR5ALDH1A1SCN4AMEN1TSHR | |
| SCHEMBL16301219 | 0.81 | S1PR5 (0.77) | S1PR5ALDH1A1SCN4AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749966-A1 | 5-HT 3 RECEPTOR AGONIST, NOVEL THIAZOLE DERIVATIVE, AND INTERMEDIATE THEREFOR | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-12-27 | — | — | EP | claimed |
| US-5834499-A | TREATING GASTROINTESTINAL DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0749966-A1 | 5-HT 3 RECEPTOR AGONIST, NOVEL THIAZOLE DERIVATIVE, AND INTERMEDIATE THEREFOR | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |