SCHEMBL8688741

SCHEMBL8688741

Nc1cc([N+](=O)[O-])cc2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.66
TSHR P16473 2/20 0.66
CYP3A4 P08684 3/20 0.53
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.51
ALDH1A1 P00352 5/20 0.46
CASP6 P55212 1/20 0.46
GAA P10253 1/20 0.46
THRB P10828 1/20 0.46
MAPT P10636 1/20 0.45
GFER P55789 1/20 0.45
GPR35 Q9HC97 1/20 0.44
PTPN1 P18031 1/20 0.44
LMNA P02545 1/20 0.43
ALOX5 P09917 2/20 0.43
PTGES O14684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8686354 0.80 TDP1 (0.52) TDP1TSHRCYP3A4MEN1KMT2A
SCHEMBL31447779 0.80 TDP1 (0.52) TDP1TSHRCYP3A4MEN1KMT2A
SCHEMBL29475186 0.79 TDP1 (1.00) TDP1TSHRCYP3A4MEN1KMT2A
SCHEMBL57381 0.79 TDP1 (1.00) TDP1TSHRCYP3A4MEN1KMT2A
SCHEMBL10688399 0.78 TSHR (0.66) TDP1TSHRCYP3A4MEN1KMT2A
SCHEMBL4960980 0.78 TDP1 (0.66) TDP1TSHRCYP3A4MEN1KMT2A
Methane SCHEMBL28603558 0.78 TDP1 (0.96) TDP1TSHRCYP3A4MEN1KMT2A
SCHEMBL1378334 0.78 TDP1 (0.66) TDP1TSHRCYP3A4MEN1KMT2A
SCHEMBL17599539 0.78 TSHR (0.66) TDP1TSHRCYP3A4MEN1KMT2A
SCHEMBL30065083 0.78 TSHR (0.66) TDP1TSHRCYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118004997-A Preparation method of pore-diameter-adjustable porous carbon material 东南大学 2024-05-10 CN claimed
WO-2025043967-A1 PREPARATION METHOD FOR AND USE OF NANOPOROUS CARBON MATERIAL HAVING CONTINUOUS STRUCTURE 东南大学 2025-03-06 WO disclosed
CN-118515261-A Preparation method of nano porous carbon material with continuous structure and application of nano porous carbon material as heat insulation material 东南大学 2024-08-20 CN disclosed
CN-118004997-A Preparation method of pore-diameter-adjustable porous carbon material 东南大学 2024-05-10 CN disclosed
CN-117088357-A Preparation method and application of nano porous carbon material with continuous structure 东南大学 2023-11-21 CN disclosed
US-7223786-B2 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2007-05-29 US disclosed
US-7223786-B2 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2007-05-29 US disclosed
US-5811492-A HAVING EXCELLENT HEAT, FIRE, CHEMICAL AND IMPACT RESISTANCE, MECHANICAL STRENGTH, AND MOLDABILITY; CONTAINING AMINO GROUPS, HYDROGENATED BLOCK COPOLYMER AND A POLYAMIDE RESIN GENERAL ELECTRIC COMPANY (US) 1998-09-22 US disclosed