SCHEMBL868995

SCHEMBL868995

CCCC=CC(OC)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3366704 1.00
SCHEMBL5815237 0.85 MEN1 (0.38)
SCHEMBL9113984 0.85 MEN1 (0.38)
SCHEMBL7590480 0.81 MEN1 (0.48)
SCHEMBL7590475 0.81 MEN1 (0.48)
SCHEMBL21670665 0.80 PTGS1 (0.32)
SCHEMBL21967104 0.80 PTGS1 (0.32)
SCHEMBL21670650 0.80 PTGS1 (0.32)
SCHEMBL20536664 0.77
SCHEMBL20536665 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
EP-3959993-B1 METHOD FOR SOLVENT FREE PRODUCTION OF AROMA CONCENTRATES SYMRISE AG (DE) 2022-12-14 EP disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
EP-3959993-A1 METHOD FOR SOLVENT FREE PRODUCTION OF AROMA CONCENTRATES Symrise AG (DE) 2022-03-02 EP disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 US disclosed
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 EP disclosed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 US disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed
EP-2287158-B1 Ambergris Odorous Substance based on 9-Methanoazuleno(5,6-d)-1,3-dioxoles SYMRISE AG (DE) 2012-11-14 EP disclosed
US-20120077722-A1 AMBERGRIS FRAGRANCE SYMRISE AG (DE) 2012-03-29 US disclosed
EP-2287158-A1 Ambergris Odorous Substance based on 9-Methanoazuleno(5,6-d)-1,3-dioxoles Symrise AG (DE) 2011-02-23 EP disclosed
EP-1617812-B1 PHOTORESPONSIVE FRAGRANCES PHO DERMA INC (US) 2010-10-06 EP disclosed
US-7176177-B2 Aromas and aroma compositions containing 4,8-dimethyl-3,7-nonadien-2-one, and a method for the production thereof SYMRISE GMBH & CO. KG (DE) 2007-02-13 US disclosed
EP-1617812-A2 PHOTORESPONSIVE FRAGRANCES Pho Derma, Inc. (US) 2006-01-25 EP disclosed
US-20050020459-A1 Carrier solution for cleaning purposes or topical applying SOLARBRE, INC. 2005-01-27 US disclosed
WO-2004084853-A2 PHOTORESPONSIVE FRAGRANCES PHO DERMA, INC. (US) 2004-10-07 WO disclosed
US-20030096731-A1 Aromas and aroma compositions containing 4,8-dimethyl-3,7-nonadien-2-one, and a method for production thereof SYMRISE AG (DE) 2003-05-22 US disclosed