Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | KLK8 | O60259 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | KLK2 | P20151 | 2/20 | 0.44 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370393 | 0.92 | SRC (0.52) | SRCKLK8PLAUKLK2KLK4 | |
| SCHEMBL2595713 | 0.90 | SRC (0.54) | SRCKLK8PLAUKLK2KLK4 | |
| Hydrochloric Acid SCHEMBL7526008 | 0.88 | SRC (0.48) | SRCKLK8PLAUKLK2KLK4 | |
| SCHEMBL1822019 | 0.83 | SRC (0.56) | SRCKLK8PLAUKLK2KLK4 | |
| SCHEMBL28670781 | 0.83 | KLK8 (0.47) | SRCKLK8PLAUKLK2KLK4 | |
| SCHEMBL4453721 | 0.83 | SRC (0.48) | SRCKLK8PLAUKLK2KLK4 | |
| SCHEMBL10632904 | 0.83 | CETP (0.49) | L3MBTL1 | |
| SCHEMBL11146084 | 0.82 | SRC (0.50) | SRCKLK8PLAUKLK2KLK4 | |
| SCHEMBL23650048 | 0.81 | CETP (0.51) | — | |
| SCHEMBL12564833 | 0.81 | CETP (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789436-A | ARTERIOSCLEROSIS; INHIBITORS OF OXIDATION OF LOW DENSITY LIPOPROTEINS; | CHUGAI SEIYAK KABUSHIKI KAISHA (JP) | 1998-08-04 | — | — | US | disclosed |