Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.60 |
| ▸ | PPARG | P37231 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687856 | 0.91 | FFAR1 (0.60) | FFAR1PPARGALDH1A1NPSR1MAPT | |
| SCHEMBL8686619 | 0.89 | FFAR1 (0.57) | FFAR1PPARGALDH1A1NPSR1MAPT | |
| SCHEMBL14406531 | 0.83 | FFAR1 (0.53) | FFAR1PPARGALDH1A1NPSR1MAPT | |
| SCHEMBL8685001 | 0.80 | FFAR1 (0.58) | FFAR1PPARGALDH1A1NPSR1MAPT | |
| SCHEMBL8690479 | 0.78 | KDM4C (0.42) | FFAR1PPARGALDH1A1MAPTRORC | |
| SCHEMBL8685774 | 0.78 | FFAR1 (0.50) | FFAR1PPARGMAPTPPARACA2 | |
| SCHEMBL6866703 | 0.77 | PPARG (0.71) | FFAR1PPARGALDH1A1NPSR1MAPT | |
| SCHEMBL8686793 | 0.76 | FFAR1 (0.47) | FFAR1PPARGALDH1A1NPSR1MAPT | |
| SCHEMBL8932654 | 0.76 | PPARG (0.47) | FFAR1PPARGALDH1A1NPSR1MAPT | |
| SCHEMBL29547028 | 0.75 | FFAR1 (1.00) | FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |