Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10278513 | 0.81 | KDM1A (0.50) | KDM1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL10254379 | 0.80 | KDM1A (0.49) | KDM1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL10864316 | 0.80 | KDM1A (0.46) | KDM1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL30841845 | 0.79 | KDM1A (0.48) | KDM1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL10288360 | 0.79 | KDM1A (0.48) | KDM1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL24468397 | 0.79 | KDM1A (0.48) | KDM1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL27469976 | 0.79 | KDM1A (0.48) | KDM1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL30471983 | 0.79 | KDM1A (0.48) | KDM1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL1311336 | 0.79 | KMT2A (0.47) | KDM1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL2550872 | 0.79 | KMT2A (0.52) | KDM1AMAOAMAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5833885-A | LENSES, ULTRAVIOLET RADIATION PROTECTION | PILKINGTON PLC (GB) | 1998-11-10 | — | — | US | disclosed |
| EP-0713491-A1 | SPIRO(INDOLINO) OXAZINE PHOTOCHROMIC COMPOUNDS | PILKINGTON PLC (GB) | 1996-05-29 | — | — | EP | disclosed |
| WO-1995005385-A1 | SPIRO(INDOLINO) OXAZINE PHOTOCHROMIC COMPOUNDS | PILKINGTON PLC (GB) | 1995-02-23 | — | — | WO | disclosed |