Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | ACR | P10323 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848431 | 0.87 | PPARG (0.54) | CYP3A4LMNAPRSS1ACRATM | |
| SCHEMBL12469535 | 0.86 | ATM (0.50) | LMNAPRSS1ACRATMKDM4E | |
| Hydrochloric Acid SCHEMBL11848416 | 0.86 | PPARG (0.52) | CYP3A4LMNAPRSS1ACRATM | |
| SCHEMBL9254070 | 0.85 | ATM (0.48) | PRSS1ACRATMKDM4EMAOB | |
| SCHEMBL30116329 | 0.85 | PRSS1 (0.55) | LMNAPRSS1ACRATMKDM4E | |
| SCHEMBL11904756 | 0.85 | PRSS1 (0.55) | LMNAPRSS1ACRATMKDM4E | |
| SCHEMBL11860150 | 0.85 | PRSS1 (0.55) | LMNAPRSS1ACRATMKDM4E | |
| SCHEMBL12617322 | 0.85 | ATM (0.52) | PRSS1ACRATMKDM4EALDH1A1 | |
| SCHEMBL338192 | 0.84 | CYP3A4 (0.65) | CYP3A4LMNAACHE | |
| SCHEMBL18697300 | 0.84 | PRSS1 (0.54) | LMNAPRSS1ACRATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102977098-B | Aryl-substituted indolizine derivative and preparation method and applications thereof | UNIV SHAOXING | 2015-04-01 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| CN-102977098-A | Aryl-substituted indolizine derivative and preparation method and applications thereof | UNIV SHAOXING | 2013-03-20 | — | — | CN | claimed |
| CN-119264128-A | Thiadiazole and pyridazine parent nucleus compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2025-01-07 | — | — | CN | disclosed |
| CN-116440926-B | Modified ZnIn2S4/BiVO4Heterojunction between benzyl alcohol and CO2Application in photocatalytic carboxylation | 重庆工商大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116440926-A | Modified ZnIn 2 S 4 /BiVO 4 Heterojunction between benzyl alcohol and CO 2 Application in photocatalytic carboxylation | 重庆工商大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-113563327-A | Novel mesoionic compound and synthesis and application thereof | 东莞市东阳光农药研发有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-110981720-B | Diaryl acetate compound and preparation method thereof | 河南大学 | 2020-11-03 | — | — | CN | disclosed |
| CN-110981720-A | Diaryl acetate compound and preparation method thereof | 河南大学 | 2020-04-10 | — | — | CN | disclosed |
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| CN-108883399-A | Fenfluramine composition and preparation method thereof | 周格尼克斯国际有限公司 | 2018-11-23 | — | — | CN | disclosed |
| US-4761501-A | INTERMEDIATES FOR ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0252474-A2 | Hydrazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
| EP-0112669-B1 | PHENETHYLAMINE DERIVATIVES AND INTERMEDIATES THEREFOR | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-07-29 | — | — | EP | disclosed |
| EP-0206951-A2 | Process for the perfluoroalkylation of aromatic derivatives | RHONE-POULENC CHIMIE (FR) | 1986-12-30 | — | — | EP | disclosed |
| US-4611078-A | ANTIDEPRESSANT INTERMEDIATES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |
| US-4535186-A | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS; VENLAFAXINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0112669-A2 | Phenethylamine derivatives and intermediates therefor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-07-04 | — | — | EP | disclosed |
| US-4426536-A | Synthesis of phenylacetic acid esters | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | disclosed |
| US-4331821-A | ULTRAVIOLET RADIATION OF A VAPORIZED ALKYLBENZEN AND HALOGEN GAS MIXTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |