SCHEMBL8693159

SCHEMBL8693159

OCC(CN1CCNCC1CCCc1c[nH]c2ccc(-n3cnnc3)cc12)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 20/20 0.58
HTR1B P28222 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8693595 0.92 HTR1D (0.55) HTR1DHTR1B
SCHEMBL8693523 0.90 HTR1D (0.56) HTR1DHTR1B
SCHEMBL8470818 0.86 HTR1D (0.64) HTR1DHTR1B
SCHEMBL8662143 0.84 HTR1D (0.63) HTR1DHTR1B
SCHEMBL8659333 0.84 HTR1D (0.66) HTR1DHTR1B
SCHEMBL8472025 0.83 HTR1D (0.58) HTR1DHTR1B
SCHEMBL8693152 0.81 HTR1D (0.59) HTR1DHTR1B
SCHEMBL8470606 0.81 HTR1D (0.55) HTR1DHTR1B
SCHEMBL8471595 0.81 HTR1D (0.57) HTR1DHTR1B
SCHEMBL7475617 0.80 HTR1D (0.81) HTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5808064-A HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE MERCK & CO., INC. (US) 1998-09-15 US claimed
US-5808064-A HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE MERCK & CO., INC. (US) 1998-09-15 US disclosed