Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.69 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755284 | 0.92 | PDE4A (0.84) | PDE4APDE4DPDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7911101 | 0.91 | PDE4A (0.82) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7366088 | 0.86 | PDE4A (0.76) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7366084 | 0.86 | PDE4A (0.76) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6886690 | 0.84 | PDE4A (0.84) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1387378 | 0.84 | PDE4A (1.00) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1387472 | 0.84 | PDE4A (1.00) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1387380 | 0.84 | PDE4A (1.00) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6755361 | 0.84 | PDE4A (0.95) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7361213 | 0.84 | PDE4A (0.82) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786354-A | Tri-substituted phenyl derivatives and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED (GB) | 1998-07-28 | — | — | US | disclosed |