Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL5619208 | 0.88 | GSK3B (0.65) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL11869376 | 0.88 | GSK3B (0.65) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL17729108 | 0.86 | GSK3B (0.68) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL5667903 | 0.83 | GSK3B (0.58) | GSK3BCASP3CASP2CASP7CASP6 | |
| Anthraquinone SCHEMBL27446912 | 0.82 | MEN1 (0.50) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Phthalimide SCHEMBL11199833 | 0.82 | GSK3B (0.75) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL28946377 | 0.82 | GSK3B (0.75) | GSK3BCASP3CASP2CASP7CASP6 | |
| Tetrabuthylammonium SCHEMBL8967570 | 0.81 | GSK3B (0.56) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL17766504 | 0.80 | GSK3B (0.54) | GSK3BCASP3CASP2CASP7CASP6 | |
| Tetrabuthylammonium SCHEMBL28914816 | 0.80 | GSK3B (0.54) | GSK3BCASP3CASP2CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573882-A | Novel routes of synthesis for preparation of suvorexant | 桑多斯股份公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104230787-B | N-(1,3-dioxoisoindolin) aryl amide compound and its preparation method and application | 华东师范大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-104230787-B | N-(1,3-dioxoisoindolin) aryl amide compound and its preparation method and application | 华东师范大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-104230787-A | N-(1,3-dioxoisoindoline) aryl amide compound as well as preparation method and applications of N-(1,3-dioxoisoindoline) aryl amide compound | UNIV EAST CHINA NORMAL | 2014-12-24 | — | — | CN | disclosed |
| US-5714508-A | INHIBITORS OF ANGIOTENSIN II | ROUSSEL UCLAF (FR) | 1998-02-03 | — | — | US | disclosed |