Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 6/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799553 | 0.93 | SYK (0.50) | SYKBACE1CTSKATMCTSL | |
| SCHEMBL5729333 | 0.92 | SYK (0.51) | SYKBACE1CTSKATMCTSL | |
| SCHEMBL14256999 | 0.91 | SYK (0.52) | SYKBACE1CTSKATMCTSL | |
| SCHEMBL6840612 | 0.88 | SYK (0.53) | SYKCTSKATMCTSLCTSB | |
| SCHEMBL10899801 | 0.88 | SYK (0.52) | SYKBACE1CTSKCTSLCTSB | |
| SCHEMBL4891550 | 0.87 | SYK (0.50) | SYKBACE1CTSKATMCTSL | |
| SCHEMBL1554884 | 0.85 | SYK (0.48) | SYKBACE1CTSKATMCTSL | |
| SCHEMBL4896495 | 0.85 | SYK (0.48) | SYKBACE1CTSKATMCTSL | |
| SCHEMBL15316179 | 0.85 | BACE1 (0.61) | SYKBACE1CTSKATMCTSL | |
| SCHEMBL15003939 | 0.85 | SYK (0.51) | SYKBACE1CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804559-A | WATER SOLUBILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-08 | — | — | US | disclosed |