Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL870034 | 0.82 | EIF2AK3 (0.35) | NOTUMBCHEACHE | |
| SCHEMBL29007917 | 0.69 | NOTUM (0.46) | PARP1NOTUMBCHEACHE | |
| SCHEMBL126414 | 0.65 | PARP1 (0.56) | PARP1NOTUMBCHEACHE | |
| SCHEMBL30686938 | 0.62 | NOTUM (0.48) | NOTUM | |
| SCHEMBL1031679 | 0.62 | NOTUM (0.48) | NOTUM | |
| SCHEMBL24651185 | 0.61 | EIF2AK3 (0.36) | — | |
| Hydrochloric Acid SCHEMBL550139 | 0.61 | NOTUM (0.47) | NOTUM | |
| SCHEMBL23059970 | 0.60 | EIF2AK3 (0.37) | — | |
| SCHEMBL869108 | 0.60 | EIF2AK3 (0.49) | — | |
| Hydrochloric Acid SCHEMBL23042914 | 0.60 | EIF2AK3 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077828-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077828-A1 | CHEMICAL COMPOUNDS | BRCA1, IRS1, IGF1R | PARP1 431/4885NOTUM 2790/4885BCHE 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.