Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 9/20 | 0.60 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.53 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692487 | 0.99 | P2RY10 (0.62) | P2RY10GPR34GPR174PLA2G2C | |
| SCHEMBL8695909 | 0.85 | P2RY10 (0.53) | P2RY10GPR34GPR174PLA2G2C | |
| Dexfosfoserine SCHEMBL28615331 | 0.84 | LPAR1 (0.64) | P2RY10GPR34 | |
| SCHEMBL29238665 | 0.84 | P2RY10 (0.65) | P2RY10GPR34GPR174PLA2G2C | |
| SCHEMBL1534116 | 0.84 | P2RY10 (0.58) | P2RY10GPR34GPR174 | |
| SCHEMBL609831 | 0.84 | P2RY10 (0.65) | P2RY10GPR34GPR174PLA2G2C | |
| SCHEMBL26642945 | 0.84 | P2RY10 (0.58) | P2RY10GPR34GPR174 | |
| SCHEMBL10563085 | 0.84 | P2RY10 (0.68) | P2RY10GPR34GPR174PLA2G2C | |
| SCHEMBL10566565 | 0.84 | P2RY10 (0.68) | P2RY10GPR34GPR174PLA2G2C | |
| SCHEMBL1801499 | 0.83 | P2RY10 (0.70) | P2RY10GPR34GPR174 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554728-A | Lipid conjugates of therapeutic peptides and protease inhibitors | NEXSTAR PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | claimed |
| US-5804552-A | COMPOUND CONSISTING OF TYROSINE OR HYDROXYPROLINE LINKED TO PHOSPHOLIPID BY PHOSPHOESTER BOND THROUGH HYDROXYL GROUP; CAPABLE OF CONJUGATION WITH THERAPEUTIC PEPTIDE | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| US-5554728-A | Lipid conjugates of therapeutic peptides and protease inhibitors | NEXSTAR PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | disclosed |