Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128938 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 | |
| SCHEMBL14018365 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 | |
| SCHEMBL6140273 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 | |
| SCHEMBL133557 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 | |
| SCHEMBL6032733 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 | |
| SCHEMBL7570019 | 0.84 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 | |
| SCHEMBL14044715 | 0.83 | ESR1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 | |
| SCHEMBL4310932 | 0.83 | ESR1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 | |
| SCHEMBL4310935 | 0.83 | ESR1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 | |
| SCHEMBL14018371 | 0.83 | ESR1 (0.55) | PTGS2CYP19A1CYP11B2CYP2D6ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830972-A | PHOTOCONDUCTOR | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |