Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257515 | 1.00 | SLC6A4 (0.52) | SLC6A4MAOASLC6A2SLC6A3KDM4E | |
| SCHEMBL607041 | 1.00 | SLC6A4 (0.52) | SLC6A4MAOASLC6A2SLC6A3KDM4E | |
| SCHEMBL28529746 | 1.00 | SLC6A4 (0.52) | SLC6A4MAOASLC6A2SLC6A3KDM4E | |
| SCHEMBL8370128 | 1.00 | SLC6A4 (0.52) | SLC6A4MAOASLC6A2SLC6A3KDM4E | |
| SCHEMBL3252828 | 1.00 | SLC6A4 (0.52) | SLC6A4MAOASLC6A2SLC6A3KDM4E | |
| Hydrochloric Acid SCHEMBL8531133 | 0.98 | SLC6A4 (0.50) | SLC6A4MAOASLC6A2SLC6A3KDM4E | |
| SCHEMBL8954525 | 0.85 | SLC6A4 (0.61) | SLC6A4MAOASLC6A2SLC6A3KDM4E | |
| SCHEMBL9039099 | 0.84 | SLC6A4 (0.50) | SLC6A4MAOASLC6A2SLC6A3KDM4E | |
| SCHEMBL9658639 | 0.84 | SLC6A4 (0.50) | SLC6A4MAOASLC6A2SLC6A3KDM4E | |
| SCHEMBL8367079 | 0.84 | SLC6A4 (0.50) | SLC6A4MAOASLC6A2SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789599-A | Aziridine compounds, methods of preparation and reactions thereof | DREXEL UNIVERSITY (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0272684-B1 | DERIVATIVES OF N-(METHYLSULPHONYLPHENYLETHYL)-2-PROPENAMIDES AND THEIR USE AS ANTIBIOTICS | ZAMBON S.p.A. (IT) | 1991-06-12 | — | — | EP | disclosed |
| US-4918095-A | Compositions with antibiotic activity and their use | ZAMBON S.P.A. (IT) | 1990-04-17 | — | — | US | disclosed |
| EP-0272684-A2 | Derivatives of N-(methylsulphonylphenylethyl)-2-propenamides and their use as antibiotics | ZAMBON S.p.A. (IT) | 1988-06-29 | — | — | EP | disclosed |