⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379590 | 0.81 | — | — | |
| SCHEMBL8696476 | 0.79 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL780457 | 0.79 | — | — | |
| SCHEMBL444377 | 0.74 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL23829498 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8686131 | 0.72 | — | — | |
| SCHEMBL8686725 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8686133 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8688852 | 0.72 | — | — | |
| SCHEMBL27692046 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035677-A1 | NON-SEDATING HISTAMINE ANTAGONIST COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | BRIDGE PHARMA, INC. (US) | 1998-08-20 | — | — | WO | claimed |
| WO-1998035677-A1 | NON-SEDATING HISTAMINE ANTAGONIST COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | BRIDGE PHARMA, INC. (US) | 1998-08-20 | — | — | WO | disclosed |