Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30502990 | 0.89 | KMT2A (0.47) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL17446822 | 0.89 | PTPN1 (0.45) | MDM4TP53KMT2AHDAC1HDAC2 | |
| SCHEMBL17446680 | 0.88 | MDM4 (0.47) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL31370796 | 0.87 | HDAC1 (0.51) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL17446644 | 0.87 | HDAC1 (0.51) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL29579138 | 0.87 | MDM4 (0.49) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL5998507 | 0.87 | MDM4 (0.55) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL1738641 | 0.87 | MDM4 (0.55) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL29395463 | 0.87 | MDM4 (0.55) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL29560536 | 0.87 | MDM4 (0.55) | MDM4TP53KMT2ACASP3SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035923-A1 | PROCESS FOR CREATING MOLECULAR DIVERSITY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1998-08-20 | — | — | WO | disclosed |