Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.65 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696281 | 0.88 | CYP19A1 (0.56) | CYP19A1CYP26A1NPC1ALDH1A1RAB9A | |
| SCHEMBL8698220 | 0.86 | CYP19A1 (0.69) | CYP19A1CYP26A1NPC1 | |
| SCHEMBL8696639 | 0.86 | CYP19A1 (0.73) | CYP19A1CYP26A1 | |
| SCHEMBL10362744 | 0.85 | CYP19A1 (0.80) | CYP19A1CYP26A1MAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10540492 | 0.84 | CYP19A1 (0.78) | CYP19A1CYP26A1MAPTALDH1A1HPGD | |
| SCHEMBL8697493 | 0.83 | CYP19A1 (0.67) | CYP19A1CYP26A1 | |
| SCHEMBL8697398 | 0.79 | CYP19A1 (1.00) | CYP19A1CYP26A1 | |
| SCHEMBL10839471 | 0.77 | CYP19A1 (0.57) | CYP19A1CYP26A1MAPTNPC1ALDH1A1 | |
| SCHEMBL10837896 | 0.76 | CYP19A1 (0.56) | CYP19A1CYP26A1MAPTNPC1ALDH1A1 | |
| SCHEMBL10838943 | 0.76 | CYP19A1 (0.56) | CYP19A1CYP26A1NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |