Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2543733 | 0.88 | CA14 (0.41) | CA14HDAC6HDAC1HDAC2CA12 | |
| SCHEMBL27470232 | 0.79 | HDAC6 (0.33) | CA14HDAC6HDAC1HDAC2CA12 | |
| SCHEMBL17160806 | 0.77 | CA14 (0.40) | CA14HDAC6HDAC1HDAC2CA12 | |
| SCHEMBL30149920 | 0.77 | KDM4A (0.35) | — | |
| SCHEMBL3984281 | 0.77 | HDAC6 (0.39) | CA14HDAC6HDAC1HDAC2CA12 | |
| SCHEMBL12342815 | 0.77 | CA14 (0.53) | CA14HDAC6HDAC1HDAC2CA12 | |
| SCHEMBL13705524 | 0.77 | CA14 (0.47) | CA14HDAC6HDAC1HDAC2CA12 | |
| SCHEMBL24401196 | 0.75 | CA14 (0.41) | CA14HDAC6HDAC1HDAC2CA12 | |
| SCHEMBL381086 | 0.75 | CA14 (0.41) | CA14HDAC6HDAC1HDAC2CA12 | |
| SCHEMBL8606993 | 0.75 | HDAC6 (0.38) | CA14HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804559-A | WATER SOLUBILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-08 | — | — | US | disclosed |