Chloroacetic Acid

Chloroacetic Acid

SCHEMBL8697102

O=C(O)CCl.O=C(O)CNc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABAT P80404 1/20 0.47
ALDH1A1 P00352 6/20 0.46
MAPT P10636 3/20 0.46
CDC25A P30304 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
ERCC1 P07992 2/20 0.45
ERCC4 Q92889 2/20 0.45
FFAR1 O14842 1/20 0.44
LMNA P02545 2/20 0.44
PKM P14618 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
TRPA1 O75762 1/20 0.43
MAPK1 P28482 1/20 0.43
GSK3B P49841 1/20 0.43
HIF1A Q16665 1/20 0.43
AKR1C3 P42330 1/20 0.43
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
MITF O75030 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hypochlorous Acid SCHEMBL11153596 0.91 ABAT (0.50) ABATALDH1A1MAPTCDC25AL3MBTL1
SCHEMBL1330698 0.91 ABAT (0.53) ABATALDH1A1MAPTCDC25AL3MBTL1
Hydrochloric Acid SCHEMBL2006870 0.91 ABAT (0.53) ABATALDH1A1MAPTCDC25AL3MBTL1
SCHEMBL7785939 0.91 ABAT (0.53) ABATALDH1A1MAPTCDC25AL3MBTL1
Benzene SCHEMBL27714747 0.91 ABAT (0.53) ABATALDH1A1MAPTCDC25AL3MBTL1
Hydrochloric Acid SCHEMBL3069393 0.91 ABAT (0.53) ABATALDH1A1MAPTCDC25AL3MBTL1
SCHEMBL41828 0.91 ABAT (0.53) ABATALDH1A1MAPTCDC25AL3MBTL1
Methane SCHEMBL5247717 0.89 ABAT (0.52) ABATALDH1A1MAPTCDC25AL3MBTL1
SCHEMBL4091646 0.89 ABAT (0.52) ABATALDH1A1MAPTCDC25AL3MBTL1
SCHEMBL2573295 0.89 ABAT (0.52) ABATALDH1A1MAPTCDC25AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5767290-A PROTECTION OF AMINE BY A TOCOPHERYL RADICAL; MILD CONDITIONS FOR DEPROTECTING; SYNTHESIS OF OLIGOPEPTIDES BASF AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed
US-5684132-A DEHYDROHALOGENATION OR DESULFATION AND AMINATION TO ADD TOCOPHEROL GROUPS BASF AKTIENGSELLSCHAFT (DE) 1997-11-04 US disclosed