Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 20/20 | 0.42 |
| ▸ | HTR1B | P28222 | 20/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651312 | 0.90 | HTR1D (0.52) | HTR1DHTR1B | |
| SCHEMBL8697128 | 0.79 | HTR1D (0.54) | HTR1DHTR1B | |
| SCHEMBL8696709 | 0.75 | HTR1D (0.37) | HTR1DHTR1B | |
| SCHEMBL8648669 | 0.73 | HTR1D (0.42) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8647370 | 0.73 | HTR1D (0.43) | HTR1DHTR1B | |
| SCHEMBL8659330 | 0.72 | HTR1D (0.50) | HTR1DHTR1B | |
| SCHEMBL8649554 | 0.72 | HTR1D (0.50) | HTR1DHTR1B | |
| SCHEMBL8662141 | 0.72 | HTR1D (0.47) | HTR1DHTR1B | |
| SCHEMBL7479279 | 0.71 | HTR1D (0.79) | HTR1DHTR1B | |
| SCHEMBL8645359 | 0.71 | HTR1D (0.51) | HTR1DHTR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | claimed |
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | disclosed |