Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10025928 | 0.87 | MCHR1 (0.52) | MCHR1FFAR1 | |
| SCHEMBL10025926 | 0.86 | MCHR1 (0.52) | MCHR1FFAR1 | |
| SCHEMBL871205 | 0.85 | MCHR1 (0.44) | MCHR1 | |
| SCHEMBL871444 | 0.85 | MCHR1 (0.48) | MCHR1 | |
| SCHEMBL869766 | 0.84 | MCHR1 (0.41) | MCHR1 | |
| SCHEMBL10025925 | 0.82 | MCHR1 (0.52) | MCHR1FFAR1 | |
| SCHEMBL871206 | 0.78 | MCHR1 (0.41) | MCHR1 | |
| SCHEMBL867665 | 0.77 | MCHR1 (0.47) | MCHR1 | |
| SCHEMBL868844 | 0.77 | MCHR1 (0.49) | MCHR1 | |
| SCHEMBL869192 | 0.76 | MCHR1 (0.53) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077794-A1 | BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS | GLAXSMITHKLINE LLC (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077794-A1 | BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS | MCHR1, MCHR2, MC1R | MCHR1 1/4885FFAR1 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.